The good (or bad) news is that the majority of talent orbs do not significantly impact most ubers. This is why when I calculate effective stats from abilities like strong against or massive damage, I still utilize the non-talent orb calculations. It keeps calculations simple and organized.
That being said, it’s worth mentioning exceptions, mainly Ultra Talented ubers who are capable of wielding double orbs. This can dramatically change the effectiveness of certain abilities. An example of this is Aphrodite, where equipping double S massive damage orbs turns her 4x damage multiplier against Aliens into a 5x damage multiplier, drastically increasing her performance into being the single best offensive anti-Alien unit in the game. For the purposes of this methodology, I have decided to test and evaluate her with this optimal talent orb build to maximize her effectiveness and find her true optimistic value as a unit.
In general, talent orbs should not have an insanely drastic impact on units, but do note that I truly evaluate units at their max potential which includes optimal talent orb builds. Note this when I cover UT ubers or any other uber that can benefit greatly from talent orbs.
Talent orbs can be very expensive to both acquire and swap out, however I’ve decided to continue ignoring investment for similar reasons to level 60/ UF/ UT ubers as doing otherwise can potentially skew the placements of some ubers. This choice also allows the methodology to remain consistent.
All talent orbs are also evaluated at their maximum (S) rank to maximize effectiveness.